Class 2A East
No. 3 Southwest Onslow (10-3) at No. 2 East Bladen (12-1)
No. 5 Wallace-Rose Hill (11-1) at No. 1 Elizabeth City Northeastern (13-0)
Class 2A West
No. 4 South Columbus (12-1) at No. 1 Reidsville (13-0)
No. 3 Hendersonville (10-3) at No. 2 Burnsville Mountain Heritage (12-0)
Class 2AA East
No. 4 Randleman (11-1) at No. 1 East Duplin (13-0)
Class 1AA East
No. 6 Lakewood (11-2) at No. 3 Edenton Holmes (11-1)
Class 1A East
No. 5 Pamlico County (9-4) at No. 1 North Duplin (12-0)
Class 3AA East
No. 11 Cape Fear (10-3) at No. 2 Wilmington New Hanover (12-1)
Class 4A East
No. 4 Winterville South Central (10-2) at No. 1 Scotland (10-1)
No. 6 Wake Forest Heritage (12-1) at No. 2 Wilmington Hoggard (12-0)